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 Original Articles |
| Lipid Profile Changes in Infection of Plasmodium Vivax |
| Chul Sin, M.D.1, Dong Joon Lim, M.D.2, Tae Jin Song, M.D.3, Kyu Chul Lee, M.D.4Inbum Suh, M.D.5, Soo-Young Yoon, M.D.5 and Chae-Seung Lim, M.D.5 |
| Division of Respiratory Disease, Department of Internal Medicine1, Neurosurgery2, General Sugery3,Opthalmology4 and Clinical Pathology5, College of Medicine, Korea University, Korea |
Vol.33 Num.1 (p58~61)
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Background:Alteration in plasma lipid levels during malaria attacks was studied to evaluate the diagnstic values in vivax malaria.
Methods:The plasma levels of total cholesterol, triglycerides, HDL-cholesterol (HDL-c), and LDL-cholesterol (LDL-c) were analyzed and compared in 32 patients with vivax malaria at presentation, in 10 patients after 17-days of treatment with anti-malaria drug, and in 40 control individuals. Interrelation of lipid profile with other parameters including parasitemia level, platelet count, hemoglobin and WBC counts were analysed.
Results:In patients with malaria, serum total cholesterol, triglycerides, HDL-c and LDL-c concentrations were significantly lower than those of control subjects. None of lipid profile showed any correlation with the parasitemia level. After treatment, HDL-c was significantly elevated.
Conclusion:These results suggest that lipid profile, especially decreased of HDL-c, may be a valuable information in the diagnosis of the malaria. |
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Keywords : Plasmodium vivax, Malaria, Lipid profile, Total cholesterol, Triglycerides, HDL cholesterol, LDL cholesterol |
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