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 Original Articles |
| The Effect of Naproxen in Febrile Patients |
| Jin Tark Nho, Kun Ho Yoon, Dong Jun Park, Wan Suh Koo, Chul Min Kim, Kyu Sik Shim, Moon Won Kang |
| Department of Internal Medicine, Catholic University Medical College, Seoul, Korea |
Vol.20 Num.1 (p57~62)
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We studied the effect of Naproxen as an antipyretic agent of fever in malignancies, autoimmune disease and infectious diseases for the differentiation of causes for fever.
1) 8 out of 13 malignancies showed complete response(61.8%) and 4 showed partial response (30.7%).
2) 3 out of 6 other disease (autoimmune diseases 4 angioimmunoblastic lymph adenopathy 2) showed complete response (50%) and 2 showed partial response (33.3%).
3) Only 1 out of 13 infectious disease showed complete response (7.7%) and 10 showed no response (76.9%).
4) The complete response rate in malignancies showed statistically higher than that in infectious disease(p<0.05).
The complete response rate in malignancies showed statistically higher than that in infectious disease (p<0.05).
The complete response rate in malignancies was slightly higher than that in other disease, but there was no statistical difference between in both group (p>0.1).
These results suggested that Naproxen was an effective antipyretic in patients with cancer. It may be useful as means of differentiating fever secondary to malignancy from that due to infection.
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