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Original Articles
The Microorganisms Isolated from Blood Cultures in Febrile Patients and Antimicrobial Susceptibility
Keun Yong Park, Duk Koo Yun
Department of Internal Medicine, Keimyung University, School of Medicine, Daegu, Korea
Vol.20 Num.2 (p123~132)
The results of blood cultures in febrile patients who visited or admitted to Keimyung University Hospital during 1981~1986 were analyzed and 349 cases of blood culture positive patients were studied in respect to clinical and antibiotic sensitivity. The results were as follows.
The most frequently isolated microorganism was Salmonella and other were S. epidermidis and Pseudomonas in order of frequency.
Twenty five percent of all microorganisms were isolated in 1986 and least microorganisms (10%) were isolated in 1982.
The Salmonella was most frequently isolated in third decade and Staphylococcus as most frequently isolated below 10 years of age.
Salmonella group A and D were isolated in all seasons but Salmonella group A were more freuqently isolated at November, December, May and July. Salmonella group D were more freqently isolated at May, June and December.
The most common route of infection was gastrointestinal tract and other important routes of infection were skin, respiratory tract, but in 10% of cases, the routes were not able to identified.
Salmonella group D showed 74% sensitivity to chloramphenicol and 68% sensitivity to ampicillin, but 19% resistance to ampicillin and 10% to chloramphenicol. S. aureus showed 100% and 80% sensitivity to cephalothin and clinidamycin respectiviely but nearly all strains were resistant to ampicillin and pencillin. Gram-negative enteric bacteria showed 61% and 56% sensitivity to amikacin and gentamicin respectively but high resistance to penicillin, kanamycin and cephalothin. P. cepacia showed 83% sensitivity to chloramphenicol but very low sensitivity to other antibiotics.

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