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 Original Articles |
| In Vitro activity of Ceftazidime(Fortum) Against Pesudomonas Aeruginosa, Enterobacteriaceae and Staphylococcus aureus |
| Yunsop Chong, Hyun Ok Kim, Samuel Y. Lee |
| Department of Clinical Pathology, Yonsei University, College of Medicine, Seoul, Korea |
Vol.20 Num.3 (p213~226)
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Ceftazidime(Fortum) is a third generation cephalosporin highly active against various gram-negative bacilli. It was reported to be stable to beta-lactamases and active against gentamicin-ortobramycin-resistant Pseudomonas aeruginosa. In this study the activity of ceftazidime was compared to those of commonly used antimicrobial agents including cefoperazone, cefotaxime and four aminoglycosides. Organisms tested were isolated in 1988, from clinical specimens of patients at Yonsei Medical Center. Agar dilution and disk diffusion methods were used. Minimum inhibitory concentrations of ceftazidime were lower than those of others against Klebsiella pneumoniae, Serratia marcescens, Proteus vulgaris, P. mirabilis, Providencia, gentamicin-resistant P. aeruinosa was susceptible to ceftaxidime. It was concluded that ceftazidime may be an effective drug in the treatment of infections acquired not only in the community but also in the hospitals.
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