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Original Articles
Isolation Sites of Campylobacter pylori in Stomach
Sang-Jin Han, Jung-Mogg Kim, Wang-Soo Han, Yang-Ja Cho
Departtment of Microbiology, Hanyang University, College of Medicine, Seoul, Korea
Vol.21 Num.1 (p1~5)
Compylobacter pylori may cause gastritis and has been proposed as an etiologic factor in the development of peptic ulcer. However, it is unknown where is primary colonization sites of C. pylori. Isolation sites of C. pylori in stomach and duodenum and pathology in antrum were evaluated in 90 subjects endoscoped at Hanyang University Hospital in Seoul, Korea. C. pylori detected in biopsied specimens of 40(74%) of 54 C.. pylori-positive patients at antrum only, and 13(24%) of the same patients at antrum and body, but did not detected in duodenal biopsied specimens. Antral pathology results were chiefly found in active chronic gastritis. These findings strongly suggest that antrum is a primary colonization sites of C. pylori and the agent may be spread within stomach from the antrum.
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