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Original Articles |
Significance of Teichoic Acid Antibody Assay in Staphylococcal Bacteremia |
Gune Iil Lim, Joong Won Kim, Jung Hee Woo, Ik Chin Chang, Duk Yong Kang |
Department of Internal Medicine College of Medicine, Soon Chun Hyang University, Seoul, Korea, Department of Clinical Pathology |
Vol.22 Num.4 (p215~219)
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Differentiation of deep-seated infection from simple, transient Staphylococcus aureus septicemia is prognostically and therapeutically important.
The development of antibodies to teichoic acid was studied in 24 S. aureus bacteremic patients (8 with infective endocarditis and one epidural abscess versus 15 with simple bacteremia).
Immunodiffusion titers of >1:2 were obtained in 6/9 patients with S. aureus deep seated infection such as infective endocarditis and acute epidural abscess but in only two of 15 simple bacteremic patients.
Thus, the quantitation of teichoic acid antibodies is of great clinical value in assessing the deep-seated S. aureus infection.
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