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A Case of Mycotic Pneumonia Caused by Fusarium Species
Ji Min Kahng, Kyung Ja Han, Kyo Young Lee, Sang In Shim, Sun Moo Kim
Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea
Vol.22 Num.4 (p255~259)
Fusarium species, belonging to the class Deuteromycetes, order Moniliales, is one of the common saprohytes and plant pathogen. Currently, infection due to Fusarium species is an increasing cause of serious potentially fatal disease in patients with cancer.
Recently, we experienced a case of mycotic pneumonia caused by Fusarium species in 24 year-old male patient with refractory anemia. The patient had been undergoing chemotherapy with low dose cytosine arabinoside, until when his body temperature was checked over 39℃ with oral thrush. He was leukopenic (0.4×109/L) at the onset of infection, and the X-ray film of the chest was showing an ill-defined inhomogenous increased density on the medial side of both upper lobes including bilateral perihilar areas.
Fungus culture with broncho-alveolar lavage fluid revealed whitish filamentous colonies on Sabour명 dextrose agar at room temperature. There was slight orange-yellow pigments on the reverse, which turned brown with age. Microscopically, the organism manifested numerous fusiform, sickle-shaped, multiseptate macroconidia, consistent with Fusarium species.
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