|
 |
 Home > Available Issues |
|
|
 Original Articles |
| Detection of Human Papillomaviruses DNA in Genital and Respiratory Tract Papilloma and Study on Transmission of Viruses Using Polymerase Chain Reaction (PCR) |
| Kyoung Chan Park, Seung Yong Jung, Yoo Shin Lee, Young Min Choi, Kwang Hyun Kim |
| Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea, Department of Gynecology, Department of Otolaryngology |
Vol.23 Num.1 (p1~6)
|
|
|
Twenty genital warts and seventeen laryngeal papilloma were analysed by PCR to detect HPV DNA. Among 20 cases of condyloma, HPV6 was found in 15 cases, HPV11 in 13 cases. Both types were found in 8 cases. Among 16 cases of laryngeal papilloma, HPV6 was found in 11 cases, HPV11 in 6 cases. Both types were found in only one case. From these results, laryngeal papilloma is found to be a pure viral disease caused by HPV6 or HPV11 and also closely related to condyloma acuminatum which are caused by HPV6, 11.
DNA extracted from ervical swabs of womens with treated cervical condyloma or without any remarkable past histroly, were examined for the presence of HPV DNA. Mothers of children with condyloma and laryngeal papilloma were also included to know the possible mode of transmission. HPV DNA was found in 7 out of 21 cases of normal female and female with previous cervical condyloma history HPV DNA was also found in 2 out of 9 cases of mothers of children's condyloma and laryngeal papilloma patinets. From these results, inapparent infection of HPV6, 11 in birth canal become evident but clinical significance of presence of these virus remained to be elucidated.
|
|
|
Keywords : |
|
|
|
|
|
|
|
|
