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 Original Articles |
| The longevity of Immunofluorescent Antibody in the Patients Confirmed as Tsutsugamushi Disease |
| Jeung Hoon Lee, Beom Jin Sung, Tae Young Youn, Woo Hyun Chang |
| Department of Dermatology, College of Medicine, Chungnam National University, Daejeon, Korea, Department of Dermatology, College of Medicine, Chungbuk National University, Cheongju, Korea, Department of Microbiology, College of Medicine, Seoul National University, Seoul, Korea |
Vol.23 Num.1 (p19~23)
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To determine an antibody titer for the diagnosis of tsutsugamushi disease in Korea, the sera, which were collected from 8 patients confirmed as tsutsugamushi disease at intervals of 2 or 6 months for 2 or 3 years, were tested by indirect immunofluorescent antibody test. In all patients the antibody titers rose to 1:320~1280 by 10~20 days after onset. And then the titers declined to a mean of 1:80 by four months and to 1:10~20 by 1 year. After maintaining the titers of 1:10~20 up to 20 months, the antibodies were not detected after 2 years. Considering its occurrence only in autumn, tsutsugamushi disease in Korea could be diagnosed from an immunofluorescent antibody titer of at least 1:40.
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