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A Case of Mucormycosis of Skin and Soft Tissue in a Healthy Adult
Yoon Sang Choi, Heung Jung Woo, Se Yong Kang, Sang Won Shin, Young Gyu Hong, Woo Joo Kim, Min Ja Kim, Seung Chull Park
Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea
Vol.23 Num.1 (p55~59)
The Mucorales are ubiquitous fungi. Disease in healthy persons is very rare. In most cases, mucormycosis occurred in patients with diabetes, leukemia or lymphoma, and impaired host defense mechanisms. Frequent sites of involvement are rhinocerebral, orbital, central nervous system, pulmonary, skin and soft tissue, gastrointestinal tract, occasionally disseminated infection occur. The disease progresses and results fatal outcome without appropriate management.
In patient with cutaneous mucormycosis, systemic administration of amphotericin-B and repeated surgical debridement of necrotic tissue are satisfactory. Occasionally aggressive infection necessitated a curative amputation.
We recently encountered a 34-year-old healthy male who was managed with intravenous amphotericin-B and amputation under the diagnosis of mucormycosis of skin and soft tissue.
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