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Original Articles |
Fluconazole Effect in Treatment of Oral Candidiasis |
Chan Soo Moon, Sang Heon Lee, Wan Shik Shin, Moon Won Kang, Jong Youl Jin, Chong Won Park, Chun Choo Kim, Dong Jip Kim, Young Lim, Im Joung Yun |
Department of Internal Medicine, St. Mary's Hospital, Catholic University Medical College, Seoul, Korea, Department of Preventive Medicine, Catholic University Medical College, Seoul, Korea |
Vol.23 Num.2 (p107~111)
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The efficacy analysis of oral or intravenous fluconazole in the treatment of oropharyngeal candidiasis of 20 patients. In the pretreatment clinical assessment, 11 cases were grade II, and 9 cases were grade III. In the pretreatment oropharyngeal culture, 3 cases were 1 positive, 15 cases were 2 positive, and 2 cases were 3 positive.
Oral or intravenous fluconazole 100mg once daily were administered. In the posttreatment efficacy assessment, the clinical improvement time was 1~3 days, the clinical cure time was 3~11 days, the mean clinical effectiveness time was 5.6 days, and the mean clinical effectiveness time was 8.1 days.
Fluconazole had a few and short-term side effects that included nausea, headache, and transient liver function abnormalities.
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