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Original Articles
Fluconazole Effect in Treatment of Oral Candidiasis
Chan Soo Moon, Sang Heon Lee, Wan Shik Shin, Moon Won Kang, Jong Youl Jin, Chong Won Park, Chun Choo Kim, Dong Jip Kim, Young Lim, Im Joung Yun
Department of Internal Medicine, St. Mary's Hospital, Catholic University Medical College, Seoul, Korea, Department of Preventive Medicine, Catholic University Medical College, Seoul, Korea
Vol.23 Num.2 (p107~111)
The efficacy analysis of oral or intravenous fluconazole in the treatment of oropharyngeal candidiasis of 20 patients. In the pretreatment clinical assessment, 11 cases were grade II, and 9 cases were grade III. In the pretreatment oropharyngeal culture, 3 cases were 1 positive, 15 cases were 2 positive, and 2 cases were 3 positive.
Oral or intravenous fluconazole 100mg once daily were administered. In the posttreatment efficacy assessment, the clinical improvement time was 1~3 days, the clinical cure time was 3~11 days, the mean clinical effectiveness time was 5.6 days, and the mean clinical effectiveness time was 8.1 days.
Fluconazole had a few and short-term side effects that included nausea, headache, and transient liver function abnormalities.
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