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 Case Reports |
| A Case of Bone Cryptococcosis in a Patient with SLE |
| Sang Won Shin, Sae Yong Kang, Heung Jeong Woo, Yoon Sang Choi, Woo Joo Kim, Seung Chull Park, Chae Seung Lim, Jun Mi Kim, Yang Seuk Chae |
| Department of Internal Medicine, College of Medicine Korea University Seoul, Korea, Department of Clinical Pathology |
Vol.23 Num.3 (p201~206)
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Cryptococcosis is a systemic fungal infection by Cryptococcus neoformans. This mycosis most commonly involves central nervous system, but bone involvement may occur as many as 5~10% of the patients.
We experienced a case of bone cryptococcosis in a patient with SLE. The patient was a 28-year old woman, who diagnosed as SLE 3 years ago. She had been treated with immune suppressants such as steroid and cyclophosphamide. She noticed painful erythematous swelling on her left forearm and skin of left breast. X-ray findings showed sclerotic changes on her posterior aspect of left proximal ulnar. Pathologic and microbiologic examination revealed characteristic findings compatible with bone cryptococcosis.
The patient was treated with bone curettage and systemic amphotericin B. The clincal symptoms and bone lesion were improved significantly without sequellae.
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