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 Case Reports |
| A Case of Q Fever; Associated with Pancytopenia, Hepatitis, and Myocarditis |
| Hyo Sook Park, Eun Gyung Lee, Seung Yul Lee, Chulhl-Joo Lyu, Young Mo Son, Dong Soo Kim, Kir-Young Kim, Won Young Lee |
| Department of Pediatrics, College of Medicine, Yonsei University, Seoul, Korea, Department of Microbiology |
Vol.24 Num.1 (p45~54)
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Q fever is an acute (on occasion chronic) febrile illness caused by inhalation of coxiella burnetii, and usually manifest as a self-limited febrile illness, pneumonia, endocarditis, hepatitis, skin rashes, myocarditis, pleuropericarditis, osteomyelitis, neurologic disease, hematologic disease, or infertility and spontaneous abortion. Treatment with tetracycline, trimethoprim-sulfamethoxazole, doxycycline, or quinolone has been effective.
We experienced a case of Q fever in a 5-year-old female patient. She complained of prolonged fever, abdominal pain and arthralgia of both knee on admission. She developed hepatitis, myocarditis, congestive heart failure, hepatosplenomegaly, pancytopenia, bone marrow necrosis and disseminated intravascular coagulation. Peripheral blood cell culture revealed Coxiella burnetii and hairy cells and antibody titer to phase I antigen was 1:160 by indirect immunofluorescent antibody assay. After intravenous chloramphenicol and oral rifampin, above symptoms and complications were improved.
We presented a case of Q fever with a review of literatures.
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