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 Case Reports |
| A Case of Infection-Associated Hemophagocytic Syndrome (IAHS) |
| Hong Ok Ryoo, Gyu Hwan Kim, Dae Sik Koo, Chong Hwee Chun |
| Department of Internal Medicine, College of Medicine, Inje University, Paik Hospital, Pusan, Korea |
Vol.25 Num.1 (p71~77)
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IAHS is a rare clinicopathologic entity characterized by fever, pancytopenia, liver dysfunction and the reactive proliferation of histiocytes of histiocytes actively phagocytosing hemopoietic cells, simulating the malignant histiocytosis, but distinct in that the phagocytosing histiocytes are morphologically mature and benign.
This syndrome occurs in patients who develop infections in the setting of preexisting immunological abnormlities or neoplasm, and usually runs a self-limited course, although in a minority of cases fatal outcomes ensue.
Recently, the author experienced a case of IAHS developed during immunosuppressive therapy in uveitis patient.
So we report this case with brief review of literatures.
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