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 Case Reports |
| Disseminated Tuberculosis and Aspergillosis in a Patient with Lupus Nephritis Undergoing Steroid 'Pulse' Therapy: The Clinical and Autopsy Findings |
| Jung Sung Lee, Kyong Ran Peck, Myoung Don Oh, Suhnggwon Kim, Kang Won Choe, Weon Seo Par*, Je Geun Chi*, Yong Il Kim* |
| Department of Internal Medicine, of Pathology* College of Medicine, Seoul National University, Seoul, Korea |
Vol.25 Num.2 (p167~176)
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lthough steroids have been used for a long time in the treatment of systemic lupus erythematosus (SLE), steroids may result in a major defect in host defences and increased prevalence of a wide variety of infection.
Steroid 'Pulse' therapy has been advocated for effective management of certain circumstance such as lupus nephritis, rapidly progressive glomerulonephritis, minimal change nephrotic syndrom but the use of high dose steroid is a problem because of the danger of mycobacterial and fungal infection.
We report the clinical and pathological findings of a lupus nephritis patient with fulminant course of disseminated tuberculosis and aspergillosis after steroid 'Pulse' therapy.
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