|
 |
 Home > Available Issues |
|
|
 Original Articles |
| Clinical Observations on Group A Streptococcal Bacteremia |
| Dong Woon Jun, June Myung Kim, Eung Kim, Gil Jin Jang, Chein Soo Hong |
| Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea |
Vol.25 Num.3 (p195~201)
|
|
|
Clinical Observations were made on 46 cases of group A streptococcal bactermia, admitted in Severance Hospital from January 1990 to June 1992. Following results were obtained.
1) In age and sex distribution, mean age was 31.7 years old and all age groups were affected. The male to female ratio was 1: 1. There was seasonal variation in the prevalence with fewer cases occuring in the summer months(July~October).
2) There were 30 cases (65%) of significant bacteremia, 9 cases (20%) of transient bacteremia and 7 cases (15%) of nosocomial bacteremia. And there were 35 cases (76%) of monomicrobial bacteremia and 11 cases (24%) of polymicrobial bacteremia. S. aureus was the most commonly concomitant pathogen in polymicrobial bacteremia.
3) In the clinical symtoms and signs, fever and chilling were most common. The gastrointestinal symptoms were frequently noted. There were 4 cases (9%) of cutaneous symptoms.
4) All of our patients had concomitant underlying conditions: Malignant disease was most common (14 case-30%). There were 10 cases (21%) of chronic heart disease, 7 cases (15%) of chronic lung disease, 3 cases (7%) of diabetes melitus. 3 cases (7%) of liver cirrhosis, 3 cases (7%) of pregnancy, 2 cases (4%) of puerperium, and 1 case (2%) of steroid immunosuppressive therapy. And among 14 cases of malignant disease, 9 cases (64%) had solid tumors.
5) The lower respiratory tract was the commonest portal of entry (22 case-48%). There were 6 cases (13%) of hepatobiliary-gastrointestinal tract, 5 cases (11%) of female genital tract, 4 cases (9%) of skin and 1 case of infective endocarditis. We observed 7 cases (15%) of primary (cryptogenic) septicemias and the patients with primary septicemia had a lower mean age (22.2 years old) but no sexual predisposition and no difference in mortality rate. Most patients of primary septicemia had concomitant underlying deseases.
6) The mortality rate was 17% (8 cases) and septic shock/hypotension and confusion were associated with higher rates of mortality.
|
|
|
Keywords : |
|
|
|
|
|
|
|
|
