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 Case Reports |
| A Case of Hepatic and Pulmonary Mucormycosis Occurred after Chemotherapy in a Patient with Acute Myelocytic Leukemia |
| Hyun Jin Park, Chul Weon Choi, Goo Lee, Jae Myung Yoo, Sang Won Shin, Woo Joo Kim, Jun Suk Kim, Seung Chull Park |
| Department of Internal Medicine, Dae Han General Hospital, Seoul, Korea
Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea |
Vol.25 Num.3 (p239~244)
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Mucormycosis is an uncommon opportunistic infection that produces disease in immunocompromised or diabetic patient. We experienced a case of hepatic and pulmonary mucormycosis. The patient was a 48-year-old male with AML, who received intensive remission-induction chemotherapy. In the neutropenic state after chemotherapy, we found infiltrating lesions in the lung and liver. Biopsy from both lesions revealed broad irregular non-septated hyphae with right-angle branching consistent with mucormycosis. Systemic antifungal therapy with use of intravenous amphotercin-B (0.6 mg/kg/day) was started, and followed by surgical resection of lung lesion and debridement of hepatic lesion. But the patient expired due to recurrence of leukemia and progression of mucormycosis.
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