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 Original Articles |
| Prevalence of Antibody to Cytomegalovirus by Anticomplement Immunofluorescence Test in Korean Children |
| Hoan Jong Lee, Seong Hee Jang |
| Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea |
Vol.25 Num.4 (p357~361)
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The prevalence of antibody to cytomegalovirus(CMV) increases with age, but widely varying patterns have been noted among different populations. We examined two hundred and ten sera for the prevalence and titers of antibody to CMV by anticomplement immunoflourescence test. The sera were collected from children under 15 years of age, admitted to the Seoul National University Children's Hospital for elective surgery or minor problems. Overall, 90% of the children had antibody to CMV. The prevalence and geometric mean titer of antibody were high in infants under 2 months of age, 90% and 103, respectively, and lowest in the age group of 3~11 months, 80% and 47%, respectively. The prevalence increased thereafter, reaching a plateau at 97% by 7~9 years. These data indicate that the most of Korean children were infected by CMV early in the life.
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