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 Original Articles |
| Clinical and Microbiological Characteristics of Enterococcal Bacteremia Evaluated in 27 Cases of Enterococcal Bacteremia |
| Mee Juhng Jeon, Myung Geun Shin, Young Hyu Kim, Jong Hee Shin, Dong Wook 꾜뭏 |
| department of clinical Pathology, Chonnam University Medical School and Kwang Ju Christian Hospital1, Kwangju Korea |
Vol.26 Num.1 (p47~55)
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Attention given to enterococci as one of the most important pathogens is increasing; similarly the incidence of enterococcal bacteremia also appears to be increasing. We investigated risk factors, clinical features, isolated species, and outcome according to high-level aminoglycoside resistance in 27 cases of enterococcal bacteremia retrospectively.
Isolates were E. faecalis (17 strains), E. faecium(6 strains), E. avium (2 strains) and E. hirae (2 strains). High-level resistance to gentamicin, kanamycin, and streptomycin was found at the level of 56%, 74% and 59%, respectively. Enterococcal bacteremia was most common in newborns (44% of patients). And the mean age of 14 adults (52% of patients) was 48 years. All patients had underlying conditions such as low birth weights caused by premature delivery (7 cases), postoperative states (6 cases), complicated delivery of neonates (5 cases), malignancies (4 cases). Twelve (4%) patients showed polymicrobial bacteremia. Antimicrobial therapy was done prior to enterococcal bacteremia in 19 (70%) of patients. Six (22%) of the patients died during hospitalization, but there were no fatal cases in the perinatal patients.
In summary, enterococcal bacteremia commonly occurred in perinatal and adult patients with underlying diseases. While the prognosis of perinatal patients was excellent, the mortality rate of adult patients with serious underlying diseases was 43% (6/14). However, it is uncertain whether enterococcal bacteremia was a significant cause of mortality.
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Keywords : Enterococcus, Bacteremia, High-level aminoglycoside resistance |
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