|
 |
 Home > Available Issues |
|
|
 Original Articles |
| Acinetobacter Bacteremia; Its Clinical Characteristics and Therapeutic Relevance |
| Cheol Ho Park, Sung Kyu Park, Jun Hee Woo |
| Department of Internal Medicine, Soon Chun Hyang University Hospital, Seoul, Korea |
Vol.27 Num.6 (p529~536)
|
|
|
Background : Acinetobacter bacteremia is less common due to low level of the virulence and pathogenic properties. Recently, its clinical relevance is augmented as frequent gram-negative bacterial isolates associated with a large number of immunocompromised host, invasive procedures, and increasing antibiotic resistance.
Methods : To elucidate clinical significance of Acinetobacter bacteremia, we retrospectively reviewed clinical records of 29 patients who were isolated Acinetobacter species from blood culture at Soon Chun Hyang University Hospital during 5 years from March 1990 to July 1994.
Results : Twenty three out of 29 patients belonged to true infections, remaind six belonged to pseudobacteremia or contamination. The risk factors of Acinetobacter bacteremia were hospitalization, especially in ICU, invasive procedure, recent operation, and recent antimicrobial use. The primary sites of secondary Acinetobacter bacteremia were respiratory tract(30%), wound and skin(17%), ruinary tract(9%), and intravenous catheter(9%). Primary sites were unknown in 35% of the patients. In antimicrobial susceptibility, the most susceptible agent is colistin(100%), and followed by ciprofloxacin(85%), aztreonam(80%), Acinetobacter were resistant to most aminoglycosides and cephalosporins.
Conclusion : Acinetobacter bacteremia is no longer infrequent infection in hospitalized patients, especially in immunocompromised patients as well as patients in intensive care units. The most common primary site of infection was respiratory tract. Acinetobacter isolates were resistant to multi-antimicrobial agents, especially aminogycosides and cephalosporins. However if treated with the proper antimicrobial agents, prognosis of Acinetobacter bacteremia would be favorable.
|
|
|
Keywords : Acinetobacter bacteremia, Risk factor, Resistance, Prognosis |
|
|
|
|
|
|
|
|
