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 Original Articles |
| Helicobacter pylori Antibodies in Control and Gastrointestinal Disorders Groups in Korea |
| In Ki Paik, Chong Rae Cho, Won Chang Shin* |
| Departments of Clinical Pathology and Internal Medicine*, College of Medicine, Inje University, Seoul, Korea |
Vol.28 Num.1 (p67~71)
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Background : Helicobacter pylori(H. pylori) antibody test by enzyme immunoassay is relatively simple and easy diagnostic tool, compared with traditional culture which is technically difficult, and other methods. However, the diagnostic significance of the antibody test has not been evaluated in Korea.
Methods : We tried to evaluate seropositive rate and antibody titers for H. pylori using ELISA test in 23 of controls, 12 of chronic gastritis and 44 cases of chronic gastric ulcer groups, who were diagnosed by gastrofiberoscope.
Results : There were no statistically significant differences(p＞0.5) in H. pylori antibody positivity rate and antibody titers among three groups.
Conclusion : This study suggests that H. Pylroi antibody test alone should not be used in order to correlate H. pylori infection with gastrointestinal disorders in routine health check-up, because there are high seropositive rate of H. pylori antibodies in normal adult population in Korea. Further study for ELISA test would be warranted to evaluate the significance of the antibody test in Korea.
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Keywords : Helicobacter pylori antibodies, ELISA, Gastrointestinal disorders |
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