|
 |
 Home > Available Issues |
|
|
 Original Articles |
| Focused Microbiologic Surveillance by Specific Hospital Unit to Define the Patterns of Antimicrobial Resistance |
| Seong Hee Lee, Chik Hyun Pai |
| Department of Clinical Pathology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea |
Vol.28 Num.3 (p239~244)
|
|
|
Background : Traditionally, trends in antibiotic susceptibility are detected by hospitalbased antimicrobial susceptibility derived from cumulative information generated from all clinical wards. However, these data may underestimate the bacterial resistance in high antibiotic-use wards such as the intensive care units(ICUs). To overcome this problem, focused surveillance techniques have been suggested to study the epidemiology of microorganisms, and guide for specific antimicrobial therapy. In present study, we attempted to evaluate the utility of focused surveillance in following the resistance patterns of isolates from the intensive care units.
Methods : Major pathogenic organisms recovered from clinical specimen were tested for antimicrobial susceptibility by the standard disk diffusion method or automated microdilution method in the microbiologic laboratory in Asan Medical Center during 12 months period from October 1994 to September 1995. The susceptibility patterns of isolates from patients in ICU were compared with those of isolates from general wards(NonICU).
Results : The patterns of susceptibility of Pseudomonas aeruginosa from ICU, were similar to those from nonICU. However, isolates of Staphylococcus aureus and coagulase-negative staphylococci from the ICU were significantly more resistant to cephalothin, ciprofloxacin, erythromycin, and oxacillin than those isolated from nonICU. Similarly, Enterobacter and Acinetobacter species were more resistant to ampicillin, cefotaxime, piperacillin, and aminoglycosides.
Conclusion : We concluded that focused microbiologic surveillance by specific hospital unit provide a sensitive means to identify unit-specific antimicrobial resistance patterns and is a useful guide for the specific antimicrobial therapy in hospital.
|
|
|
Keywords : Focused microbiologic surveillance, antimicrobial susceptibility patterns, intensive care units |
|
|
|
|
|
|
|
|
