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 Case Reports |
| A Case of Primary Central Nervous System Lymphoma with Acquired Immunodeficiency Syndrome |
| Eun Bong Lee, Kyong Hoon You, Myoung Don Oh, Nam Joong Kim, Chang Dal You, Han Ju Ba다, hyoung Shik Shin, Dae Seog Heo, Je Geun Chi*, Kang Won Choe |
| Department of Internal Medicine and Pathology*, Seoul National University Hospital, College of Medicine, Seoul National University, Seoul, Korea |
Vol.28 Num.4 (p367~372)
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A 43-year old man with acquired immunodeficiency syndrome was admitted to this hospital because of cognition defect. The patient with a history of homosexual behaviour developed acquired immunodeficiency syndrome seven months before this admission, when he was positive for HIV test, had cryptosporidiosis and suspicious pulmonary tuberculosis. One week before admission, fever, cognition defect, including inappropriate response and memory disturbance, and ptosis of the left eye developed. Brain MRI showed an ill-defined, rim enhancing lesion in the left mid brain and both thalami. Stereotaxic brain biopsy showed malignant lymphoma with monoclonal T cell phenotype on nested PCR and immunohistochemistry. Brain radiotherapy of 6120 rad was delivered, which resulted in stable disease. We report the first case with acquired immunodeficiency syndrome and primary central nervous system lymphoma in Korea.
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Keywords : Acquired immunodeficiency syndrome, Central nervous system lymphoma |
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