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 Case Reports |
| Two Cases of Cryptosporidium parvum Infection in AIDS Patients |
| Hyun Jae Kang, Yoon Jun Kim, Hee Jung Choi, Hyoung Shik Shin, Sung Min Kim, Myoung Don Oh, Jong-Yil Chai*, Kang-Won Choe |
| Department of Internal Medicine, Parasitology*, Seoul National University College of Medicine, Seoul, Korea |
Vol.28 Num.5 (p443~448)
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Cryptosporidium is an intracellular protozoan parasite and known as an important pathogen causing diarrheal illness in animals and man since 1970's. With the advance of epidemic of Acquired Immunodeficiency Syndrome(ADIS), Cryptosporidium has emerged as one of important pathogens in AIDS patients and is responsible for chronic diarrhea, cholecystitis, biliary tree obstruction and respiratory illness. Despite frequent reports of cryptosporidial diarrhea in other countries there has been no report of human cryptosporidial infection in AIDS patients so far in Korea. We report two cases with chronic cryptosporidial diarrheal illness in AIDS patients. C. parvum oocyst was identified by fecal smear with modified acid fast staining. In one patient the diarrheal illness was improved after 4 weeks supportive management only. But fecal excretion of oocyst continued after clinical improvement of the diarrheal illness. Another patient was died of respiratory failure after recurrent diarrheal illness. Cryptosporidial infection should be considered in differential diagnosis of chronic diarrhea especially, in AIDS patients.
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Keywords : Cryptosporidium, Diarrhea, AIDS |
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