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An Autopsy Case of the AIDS Presented with Disseminated Cryptococcosis
Koh SB, Han JK, Choi JC, Yoo SW, Kim BJ, Park MK, Park KW, Lee DH, Kim MJ, Park SC, Chae YS
Department of Neurology, College of Medicine, Korea University. Department of Internal Medicine, College of Medicine, Korea University. Department of Pathology, College of Medicine, Korea University.
Vol.29 Num.5 (p427~432)
Central nervous system cryptococcosis is common in the AIDS patients with reported incidences ranging from 1.9% to 11.0%. Cryptococcosis may be the initial manifestation of HIV infection or occur simultaneously with other opportunistic infections. HIV-infected patients with central nervous system cryptococcosis complain of fever, headache, nausea and vomiting, and cognitive dysfunction. Meningeal signs and photophobia are less common than in HIV-negative patients. Focal neurologic signs and seizures are uncommon. Disseminated cryptococcosis is often concomitantly found at the time of central nervous system cryptococcosis. We report a case of 49 year-old Korean female with HIV infection who died of disseminated cryptococcosis with autopsy findings.
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