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Original Articles
Seroepidemiologic Study of Brucellosis in Cheju Island
Joon Sup Yeom, M.D., Hei Chul Jung, M.D., Jae Hyun Nam, M.D., Young Hwa Choi, M.D., Young Goo Song, M.D., Eung Kim, M.D., Hyon Suk Kim, M.D.1, Il Suh, M.D.2 and June Myung Kim, M.D.
Department of Internal Medicine, Clinical Pathology1, Preventive Medicine and Public Health2, Yonsei University College of Medicine
Vol.30 Num.2 (p165~172)
Background:Brucellosis is a zoonosis caused by the gram-negative coccobacilli Brucella. Humans are infected by ingestion of unpasteurized milk or dairy products from or by direct contact with infected animals. Although human brucellosis is known to be rare, there has been an increase in bovine brucellosis in Cheju island since the 1980s. The purpose of this study was to investigate the prevalence of anti- Brucella antibody in people from endemic areas.
Methods:Sera obtained from 2,372 residents in Cheju island were screened for anti-Brucella antibody by slide agglutination test and confirmed by duplicated tube agglutination test. Sera with titers equal to or above 1:80 were considered positive.
Results:Fourteen of 2,372 sera were positive (0.59%). Positive rate was 0.34% in males and 0.82% in females. There was no significant difference in the positive rates between males and females. Seropositive rate was slightly ????
Keywords : brucellosis, seroepidemiology, agglutination test