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 Original Articles |
| The Methicillin-Resistance Rate of Staphylococcus aureus Isolatd from Anterior Nares of Healthy Adults in the Community |
| Hong Bin Kim/Dong Hyeon Shin/Kyung Un Park/Myoung Don Oh/Eui Chong Kim/Kang Won Choe |
| Departments of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. Departments of Clinical Pathology, Seoul National University College of Medicine, Seoul, Korea. |
Vol.30 Num.6 (p527~531)
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BACKGROUND: About 80% of nosocomial Stap hylococcus aureus isolates demonstrate methicillin resistance in Korea. To assess the prevalence of methicillin- resistant S. aureus (MRSA) in the community, we screened the nasal S. aureus isolates from healthy adults.
METHODS: Nasal cultures were collected from healthy adults without known risk factors for acquisition of MRSA. Antimicrobial susceptibility of S. aureus isolates against oxacillin were determined using the E- test and the disk diffusion method. Methicillin resistant isolates were tested for the mecA gene by polymerase chain reaction.
RESULTS: Total 689 subjects were studied. The point prevalence of S. aureus was 33% (227/689). Sixteen isolates of S. aureus grew on the MRSA screening plates(MAO), of which 5(2.2%) were resistant to oxacillin and positive for the mecA gene.
CONCLUSION: Less than 5% (95% CI; 1 ~5%) of the nasal S. aureus isolates in the community were methicillin-resistant.
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Keywords : Methicillin-resistant Staphylococcus aureus, Surveillance, Community |
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