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 Case Reports |
| A Case of Developed Tuberculous Lymphadenitis and Epstein-Barr Virus Associated Lymphadenitis |
| 1Meong Hi Yun/1Nak Gyun Chung/1Dae Chul Jeong/1Jin Tack Kim/1Seung Yun Chung/1Jin Han Kang/2Kyung Mee Kim |
| Department of Pediatrics, College of Medicine, Catholic University, Seoul, Korea. Department of Clinical Pathology, College of Medicine, Catholic University, Seoul, Korea. |
Vol.31 Num.5 (p445~449)
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Lymphadenitis is a common pediatric disease associated with infection and inflammation. Acute lymphadenitis in children is usually accompanied by systemic viral illness, and subsides within a few days to two weeks. However, chronic lymphadenopathy or lymphadenitis is a rare disease, and is due to a reactive response to infections including tuberculosis, neoplasms, and noninflammatory lesions. The diagnostic evaluation or chronic lymphadenitis may be very
complicated and it is important to consider chronic infectious diseases and are malignancies as possible etiologies. We report a 13-year old boy who was eventually diagnosed with tuberculous lymphadenitis. The patient was initially admitted for enlarged cervical, axillary, and epitrochlear lymph nodes. Biopsy of a cervical lymph node showed the findings compatible with angioimmunoblastic
lymphadenopathy with dysproteinemia (AILD) associated with EBV infection. During treatment with prednisolone, the enlarged lymph node decreased in size. However, the lymph node enlargement resumed and we performed a second biopsy. At this time the biopsy showed tuberculous lymphadenitis and a culture of gastric juice showed M. tuberculosis. With the initiation of antituberculous treatment, the patient improved clinically.
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Keywords : Epstein-Barr virus lymphadenitis, Tuberculous lymphadenitis, Angioimmunoblastic lymphadenitis with dyoproteinemia |
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