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 Original Articles |
| Viral Etiology of Community-acquired Pneumonia in Korean Adults |
| Jee Hee Kim, M.D., Ph.D.1, Young Ho Kwak, M.D.2, Byoung Kuk Na, Ph.D.1, Joo Yeon Lee1, Gu Choul Shin1, He Sun Jung, M.D.2, Jung Youn Hong, M.D.2†, Myoung Don Oh, M.D.3, Hee Jin Cheong, M.D.4, Min Ja Kim, M.D.4, Hyun Joo Pai, M.D.5, Yang Ree Kim, M.D.6, Wan Shik Shin, M.D.6, Jae Myung Kang, M.D.7, Jun Hee Woo, M.D.7, Soo-Taek Uh, M.D.8, and Hoan Jong Lee, M.D.2 |
| National Institute of Health1, Department of Internal Medicine, College of Medicine, Korea University4, Dankook University5, the Catholic University of Korea6, Ulsan University7, Soonchunhyang University8, Department of Pediatrics2 and Internal Medicine3, College of Medicine, Seoul National University, Seoul, Korea |
Vol.33 Num.1 (p8~14)
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Purposes:To investigate the viral etiology of community-acquired pneumonia in Korean adults, we have detected respiratory viruses (Respiatory syncytial virus, adenovirus, influenza virus and parainfluenza virus) in the way of prospective, multi-center study.
Methods:From July 1997 to April 2000, nasal aspirates or sputum were obtained from adults patients with community pneumonia admitted to the participating hospitals and transferred immediately to the central laboratory at the Seoul National University Children's Hospital. The specimens were divided into three parts. One part was used for indirect immunofluorescent test for respiratory viruses, the other part for the culture of RSV and adenovirus in HEp-2 cell monolayer. The other part was used for the culture of influenza virus and parainfluenza virus in MDCK or LLC- MK2 cell monolayers.
Results:Of 317 samples, 32 (10.1%) specimens were positive for viral agent by indirect IF staining or culture, including one dual-infected specimen (adenovirus and parainfluenza virus). Influenza virus was most commonly detected (16 specimens). Parainfluenza virus, adenovirus and RSV were detected in 10, 4 and 3 patients, respectively. All isolated influenza viruses were type A (H3N2 in 9 patients, H1N1 in 2 and unspecified in 5), and 8 out of 10 parainfluenza virus isolates were type 3.
Conclusion:Similar to previous reports from other countries, a significant portion of community-acquired pneumonia in Korean adult is caused by respiratory viruses. |
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Keywords : Pneumonia, Respiratory virus |
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