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Lethal Measles Pneumonia after Allogenic Hematopoietic Stem Cell Transplantation
Chang-Nyol Paik, M.D., Dong-Gun Lee, M.D., Hyun-Wha Jung, M.D., Jung-Hyun Choi, M.D. Yu-Kyung Cho, M.D., Hoon-Jun Park, M.D., Seung-Hoon Lee, M.D., Yoon-Hee Park, M.D. Kyo-Young Lee, M.D., Wan-Sik Shin, M.D., Woo-Sung Min, M.D. and Chun-Choo Kim, M.D.
Department of Internal Medicine and Clinical Pathology*, College of Medicine, The Catholic University of Korea, Seoul, Korea
Vol.33 Num.4 (p305~309)
As a result of the enlarging pool of unvaccinated children and young adults, there has been an increase in measles in our countries. In these situation, it has been reported that measles associated pneumoinia is easily complicated with fatal respiratory failure, especially in immunocompromised patients. Herein we report the case of lethal measles pneumonia after allogenic hematopoietic stem cell transplantation in adults proven by autopsy.
Recently, one case of measles was encountered in 39-year-old female patients after allogenic bone marrow transplanted case (chronic myelogenous leukemia), who progressed into interstitial pneumonia pattern, despite treatment including antibiotics, immunoglobulin. The patient died of giant cell pneumonia compatible with that of measles which was comfirmed in the section of necropsy lung specimen.
Keywords : Pneumonia, Measles, Bone marrow transplantation