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 Case Reports |
| A Case of Azithromycin Therapy for Tsutsugamushi Disease During Pregnancy |
| Kwang-Seok Kim, M.D., Jin-Wook Choi, M.D., Ho-Jong Seo, M.D.*, Ki-Hoon Kim, M.D.*
Sung-Ho Park, M.D.*, Kwang-Seob Seo, M.D.*, Sung-Maan Ko, M.D.
Soon-hye Kim, M.D. and Ho-Jung Kim, M.D. |
| Department of Internal Medicine, Sung Ae Hospital, Seoul, Department of Internal Medicine,
Kwangmyung Sung Ae Hospital*, Kwangmyung, Korea |
Vol.33 Num.5 (p380~382)
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We report a case of tsutsugamushi disease in a 26 year-old pregnant woman who was treated with azithromycin. Her gestation period was 27 weeks and she admitted with fever, rash, and eschar on the right shoulder. Currently recommended medications for the treatment of scrub typhus are doxycycline or chloramphenicol. But, these drugs are class D drugs according to the U.S. Food and Drug Administration (FDA) Fetal Risk Summary, so, they couldn't be used to treat pregnant women. Recently, a few case reports suggested that azithromycin, a relatively new macrolide antibiotic, was effective and safe for the treatment of scrub typhus infected pregnant women. And, there is no evidence that azithromycin causes harmful effects to the developing fetus or to children. On the basis of current in vivo test that confirms the effectiveness of azithromycin, it may be the drug of choice for the treatment of scrub typhus in pregnant women and children. |
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Keywords : Tsutsugamushi disease, Scrub typhus, Azithromycin, Pregnancy |
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