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Scrub Typhus in a Pregnant Woman : No Evidence of Intrauterine Infection
Ji-Hwan Bang, M.D., Young-Ju Choe, M.D., Yo-Han Joh, M.D. Ui-Seok Kim, M.D., Jong-Wook Shin, M.D., Hang-Rae Kim, D.V.M.* Myoung-Don Oh, M.D., Ik-Sang Kim, M.D.* and Kang-Won Choe, M.D.
Department of Internal Medicine, Department of Microbiology and Immunology*, Seoul National University College of Medicine, Seoul, Korea
Vol.33 Num.6 (p453~455)
Pregnancy with scrub typhus is a rare condition. A 30-year-old woman was infected with scrub typhus at the 35th week of gestation. She was treated successfully with azithromycin, and delivered her baby uneventfully. The baby developed no signs for scrub typhus, and thrived well. IgM antibodies to O. tsutsugamushi were undetectable in the baby's sera, and titers of IgG antibodies did not rise. The polymerase chain reaction of the cord blood for O. tsutsugamushi was also negative. We concluded that transplacental infection did not occur in this pregnant woman.
Keywords : Scrub typhus, Pregnancy, Vertical transmission, Azithromycin