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 Case Reports |
| A Case Report of Postoperative Herpes Simplex Viral Pneumonia in a Patient with Tracheal Adenoid Cystic Carcinoma |
| Jae Chul Hwang/Young Hwa Choi/Hye Jiin Cho/Yoon Jung Oh/Hyunee Yim/Kwang Joo Park/Yi Hyeong Lee |
| Department of Pulmonology and Critical Care Medicine, Ajou University School of Medicine, Suwon, Korea. |
Vol.34 Num.1 (p64~68)
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Herpes simplex virus (HSV) infection of the lower respiratory tract occurs rarely in neonate and immunocompromised host. The need for a timely and specific diagnosis of viral infections is becoming greater with development of antiviral
chemotherapy. Herein, we report a case of herpes simplex virus pneumonia diagnosed by cytologic examination of the bronchoalveolar lavage (BAL) sampe of respiratory epithelial cells in a tracheal adenoid cystic carcinoma patient. A 65-year-old woman presented with dyspnea and cough for one month. Bronchoscopy showed a mass arising from the posterior wall of upper trachea, and she underwent tracheal sleeve resection with cricotracheal anstomosis. The pathologic examination revelaed adenoid cystic carcinoma. Corticosteriods were used for prevention of stenosis and swelling on the anastomosis site On 28th postoperative day, pneumonia developed and it was aggravated despite of antibiotic therapy. The cytologic examiniation of the BAL fluid showed the eosinophilic nuclear inclusion along with the positive result of immunocytochemistry using monoclonal antibody toe HSV. Despite of immediate therapy with acyclovir the pneumonia progressed to the acute respiratory distress syndrome and the patients eventual died.
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Keywords : Herpes simplex virus, Pneumonia, Adenoid cystic carcinoma, Steroid, Bronchoalveolr lavage |
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