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A Case of Septicemia by Transient Glycopeptide-Dependent Enterococcus faecium
Soo Young Kim/Seok Jin Kang/Seung Ok Lee/Wee Gyo Lee/Yeon Joon Park/Byung Kee Kim
Department of Clinical Pathology , College of Medicine, The Catholic University of Korea, Seoul, Korea.
Vol.34 Num.1 (p69~72)
The isolation of clinical strains of enterococci requiring vancomycin for growth has been reported, but transient strain has not been reported. Transient glycopeptide-dependent enterococcus faecium was isolated from the blood of a 59-year-old
female with advanced rectal carcinoma during long term broad-spectrum antirectal carcinoma during long term broad-spectrum antimicrobial therapy. This strain showed transient glycopeptide dependency, but glycopeptide-resistant revertants were found on subculture to blood agar without vancomycin. It was found to be the vanA genotype by the polymerase chain reaction analysis.
Keywords : Glycopetide-dependent Enterococcus faecium, vanA