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A Case of Progressive Multifocal Leukoencephalopathy in a Patient with Acquired Immune Deficiency Syndrome
Jung Min Lee, M.D.*, Yoon Seon Park, M.D.*, Suk Hoon Choi, M.D.*, Sang Hoon Han, M.D.*, Bum Sik Chin, M.D.*, So Youn Shin, M.D.*, Jun Yong Choi, M.D.*,†, Kkot Sil Lee, M.D.*,†, Yoon Soo Park, M.D.*,† Cheong Ho Cho, M.D.*,†, Kyung Hee Chang, M.D.*,†,
Department of Internal Medicine* and AIDS Research Institute†, Yonsei University College of Medicine, Seoul, Korea
Vol.36 Num.1 (p50~53)
In Korea, as the prevalence of acquired immune deficiency syndrome (AIDS) increases, various opportunistic infections are becoming a problem. Progressive multifocal leukoencephalopathy (PML) is postulated to be associated with impaired cellular immunity and can be more frequently encountered these days primarily due to increasing incidence of AIDS. Neurologic deficits and brain imaging study together strongly suggest PML, but confirmatory diagnosis can be made only by cerebrospinal fluid study or tissue biopsy. In Korea few cases of confirmed PML in AIDS patients have been reported, and herein we offer our experience of a case of PML who underwent brain biopsy for confirmative diagnosis.
Keywords : Progressive multifocal leukoencephalopathy, AIDS, HIV