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A Case of Cerebral Toxoplasmosis in a Patient with Acquired Immune Defeciency Syndrome
Bo Hyun Kim, M.D.1, Sung Ik Lee, M.D.1, Chang Hun Lee, M.D.2, Sung Heun Cha, M.D.3, Tae Hong Lee, M.D.4, Sun Hee Lee, M.D.1, Joo Seop Chung, M.D.1, and Goon Jae Cho, M.D.1
Department of Internal Medicine1, Pathology2, Neurosurgery3, Diagnostic Radiology4 College of Medicine, Pusan National University, Busan, Korea
Vol.36 Num.3 (p181~184)
Toxoplasmosis is one of the most common opportunistic infection of the central nervous system in patients with acquired immunodeficiency syndrome(AIDS). There have been few reports of cerebral toxoplasmosis in patients with AIDS in Korea. In most cases, the diagnosis was assisted by serology and neuroradiologic findings. Making a reliable diagnosis of acute cerebral toxoplasmosis is difficult in patients with AIDS because of the lack of specificity of serologic data and neuroradiological findings. We report a case of 32-year-old man who presented with decreased mentality and fever. Brain MRI showed multiple ill-defined mass-like lesions in both basal ganglia and right thalamus. Stereotatic brain biopsy revealed small parasitic cysts which were filled with toxoplasmic bradyzoites in inflammatory brain tissue.
Keywords : Cerebral toxoplasmosis, AIDS