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A Case Report on Cryptococcal Lymphadenitis in an Immunocompetent Adult Patient
Jong Jin Hyun, M.D.1, Jong Hwan Choi, M.D.1, Sanghoon Park, M.D.1, Hye Won Jeong, M.D.1 Sung Joo Jung, M.D.1, Sae Yoon Kee, M.D.1, Hee Jin Cheong, M.D.1, Woo Joo Kim, M.D.1 Jung Woo Choi, M.D.2, Joo Han Lee, M.D.2, Na Ri Lee, M.D.3 and Soung Ming Jeon, M.
Division of Infectious Disease, Departments of Internal Medicine1, Pathology2, Korea University College of Medicine Department of Internal Medicine3, Sam An Yang Hospital, Seoul, Korea
Vol.37 Num.6 (p350~354)
Cryptococcus neoformans is an organism that mainly causes opportunistic infection in immunocompromised patients. It can also cause various infections in immunocompetent patients, but cryptococcal lymphadenitis is rare. We have experienced a case of cryptococcal lymphadenitis in an immunocompetent adult patient who presented with cervical lymphadenopathy and fever that did not subside for 3 weeks. Neck and chest CT scan showed multiple lymph node enlargements with central low density and peripheral enhancement on both hilar, mediastinal, and right supraclavicular areas. Cryptococcus lymphadenitis was diagnosed by tissue biopsy, PAS and GMS stain, and culture. This case emphasizes that when an immunocompetent patient presents with lymphadenopathy, cryptococcal lymphadenitis should always be considered in the differential diagnosis.
Keywords : Cryptococcus neoformans, Cryptococcal lymphadenitis, Immunocompetent patient