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A Case of Rhabdomyolysis in a Patient with Plasmidium vivaxMalaria Treated with Hydroxychloroquine
Se Jin Jung, M.D.1, Yeon-A Kim, M.D.1, Jeehoon Ghil, M.D.1, Nam Su Ku, M.D.1, Joon Hyung Kim, M.D.1Yoon Sun Park, M.D.1,2, Myung Soo Kim, M.D.1,2, Young Keun Kim, M.D.1,2, So Youn Shin, M.D.1,2Jun Yong Choi, M.D.1,2 and June Myung Kim, M.D.1,2
1Department of Internal Medicine, 2AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea
Vol.38 Num.3 (p174~178)
Rhabdomyolysis is a potentially life-threatening syndrome resulting form the breakdown of skeletal muscle fibers with leakage of muscle contents into the circulation. Rhabdomyolysis may complicate many disease states. In some cases, patients with malaria may be complicated with rhabdomyolysis. Also hydroxychloroquine may induce myopathy and rhabdomyolysis. But there is no case report of rhabdomyolysis after use of hydroxychloroquine in a Korean patient with Plasmodium vivax malaria. Recently we experienced a patient who developed rhabdomyolysis 20 days after starting therapy with hydroxychloroquine for the treatment of P. vivax malaria. We report the case with the review of the literature.
Keywords : Rhabdomyolysis, Plasmodium vivax, Malaria, Hydroxychloroquine