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 Case Reports |
| A Case of Kikuchi-Fujimoto Disease Presenting as Mesenteric Lymphadenitis |
| Won Sub Choi, M.D.1, Seung Soon Lee, M.D.1, Chin Woo Kwon, M.D.1, Young Seok Lee, M.D.1Sun Young Kim, M.D.1, Sun-young Cheon, M.D.2, Min-Jeong Kim, M.D.3 and Doo Ryeon Chung, M.D., Ph.D.1 |
| Department of Internal Medicine1, Department of Pathology2 and Department of Radiology3, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang-si, Korea |
Vol.38 Num.5 (p304~307)
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Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is a benign, rare, self limitimg disease presenting with mainly cervical lymphadenopathy and fever unresponsive to antibiotics or medical treatment. A 28-year old man presented with fever and right lower quadrant abdominal pain. Physical examination showed abdominal tenderness and rebound tenderness mimicking acute appendicitis. Imaging studies showed normal appendix and other abdominal organs except enlarged multiple mesenteric lymph nodes. Symptoms persisted despite antimicrobial therapy. Multiple tender lymph nodes were palpable on bilateral cervical area at the 7th hospital day. The biopsy of the neck node showed large areas of patchy, irregular necrosis with prominent nuclear debris surrounded by T lymphocytes, histiocytes without neutrophils and granuloma, so he was diagnosed as Kikuchi- Fujimoto disease. With conservative management, clinical improvement was observed. We suggest that Kikuchi-Fujimoto disease with mesenteric lymphadenitis should be added to the differential diagnosis of acute abdomen mimicking acute appendicitis in young adults. |
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Keywords : Kikuchi-Fujimoto disease, Histiocytic necrotizing lymphadenitis, Mesenteric lymphadenitis |
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