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Case Reports |
A Case of Cytomegalovirus Enterocolitis and Jejunal Perforation During
Immune Reconstitution with Highly Active Antiretroviral Treatment |
Se Ho Choi, M.D.1, Hyo Sung Kang, M.D.1, Sung Ho Lee, M.D.1, Jong Hyun Lee, M.D.1, Kyung Youn Seon, M.D.1
Seung Woo Nam, M.D.1, Jae kwan Hwang, M.D.2 and Hyoung Shik Shin, M.D.1 |
Departments of Internal Medicine1, General Surgery2, National Medical Center, Seoul, Korea |
Vol.38 Num.6 (p398~402)
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Immune reconstitution syndrome (IRS) in HIV-infected patients is an adverse consequence of the restoration of pathogen-specific immune responses during the initial months of highly active antiretroviral treatment(HAART). Previously subclinical infections are unmasked or pre-existing opportunistic infections clinically deteriorate as host immunopathological inflammatory responses are switched on. While the eye is the area where Cytomegalovirus(CMV)-associated IRS occurs most often in patients with AIDS, it also can present with intestinal or pulmonary involvement. We present a case report of an HIV-infected patient in whom CMV enterocolitis and jejunal perforation developed after HAART. |
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Keywords : Cytomegalovirus, Enterocolitis, Immune reconstitution syndrome, Highly active antiretroviral therapy |
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