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Spontaneous Bacterial Peritonitis due to Brucella abortus in a Cirrhotic Patient in Jeju Island
Sang Taek Heo, M.D.1, Yoo Kyung Cho, M.D.1, Young-Ree Kim, M.D.2, Keun Hwa Lee, Ph.D.3, Ji Won Yoon, M.D.4 Kwan Soo Ko, Ph.D.5, Mi Yeoun Park, Ph.D.6 and Young Sill Choi, Ph.D.6
Department of Internal Medicine1, Laboratory Medicine2 and Microbiology3, Cheju National University HospitalCheju National University of Medicine; Department of Internal Medicine4, Seoul National University Hospital5Asian-Pacific Research Foundation for
Vol.39 Num.1 (p54~58)
Spontaneous bacterial peritonitis is the common infectious disease in liver cirrhosis patients with a fever. Brucellosis is a rare cause of bacterial peritonitis. A case indigenous to a citizen of Jeju, he ate a raw veal of cow four times in last 2 months prior to admission. The gram-negative bacilli were isolated from blood and peritoneal fluid cultures. He was confirmed brucellosis by serologic work- ups. This isolate was confirmed as Brucella abortus by using PCR amplification of 16S ribosomal RNA (rRNA) and omp2. This is the first case of bruellosis that was diagnosed spontaneous bacterial peritonitis in liver cirrhosis patient among native korean citizens. Successful treatment was obtained by using a regimen of doxycycline and gentamicin. Brucella should be suspected as a cause of spontaneous bacterial peritonitis in cirrhotic patients with no response to standard spontaneous bacterial peritonitis treatments.
Keywords : Brucellasis, Spontaneous bacterial peritonitis, Jeju island