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A case of Agrobacterium radiobacter Sepsis following Oral Surgery in a Patient of Oral Cancer
Su Jin Jeong, M.D.1, Hee Kyung Choi, M.D.1, Hye Won Lee, M.D.1, Sang Hoon Shin, M.D.1, Chang Ki Kim, M.D.1,3, Han Sung Lee, M.D.1,2, Bum Sik Chin, M.D.1,2, Suk Hoon Choi, M.D.1,2, Sang Hoon Han, M.D.1,2, Myung Soo Kim, M.D.1,2, Chang Oh Kim, M.D.1,2, Jun Yong Choi, M.D.1,2, Young Goo Song, M.D.1,2 and June Myung Kim, M.D.1,2
Department of Internal Medicine1, AIDS Research Institute2, Yonsei University College of Medicine, Seoul, Department of Laboratory Medicine3, Yonsei University College of Medicine, Seoul
Vol.39 Num.5 (p270~273)
Agrobacterium is an aerobic, motile, oxidase-positive, and non-spore-forming gram-negative bacillus. Under laboratory conditions, Agrobacterium can genetically transform a wide range of other eukaryotic species. A plant-pathogenic soil inhabitant, Agrobacterium radiobacter is not characterized as a true human pathogen. It is an opportunistic pathogen of minor clinical significance and has been substantiated as a rare cause of bacteremia, endocarditis, urinary tract infection and peritonitis mostly in catheterized immunocompromised patients. The authors report a case of a 41-year-old female patient with sepsis caused by A. radiobacter bacteremia following wide excisional biopsy of adenoid-cystic carcinoma involving oral cavity. She was suffering from fever and chilling that developed on second post-operation day. Blood cultures yielded a gram-negative bacillus identified as A. radiobacter. She completely recovered with appropriate antibiotics treatment; levofloxacin and isepamicin. We experienced a case of sepsis due to A. radiobacter bacteremia without indwelling foreign body, which was treated successfully with antibiotics therapy.
Keywords : Agrobacterium radiobacter, Sepsis, Fluoroquinolone