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Recent Evidences of Sepsis Treatment
Jung-Hyun Choi, M.D.
Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea
Vol.40 Num.2 (p67~75)
Severe sepsis and septic shock are conditions with a mortality rate about 50% despite of advances of antimicrobial treatment and supportive cares. Recently, investigators are trying to establish a scientific basis for identification of high-risk patients, or a standard practice for hemodynamic optimization and adjunctive pharmacologic therapies for these patients. Several randomized, controlled trials and meta-analyses about certain therapies showed significant reduction of mortality and morbidity. This article is a clinical review of contemporary management strategies recommended with evidences for severe sepsis and septic shock.
Keywords : Sepsis, Septic shock, Evidence-base medicine