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A Case of Septic Hip Arthritis Caused by Aspergillus fumigatus in a Liver Transplant Recipient
Tark Kim, M.D.1, Sang-Rok Lee, M.D.1, Oh Hyun Cho, M.D.1, Ki Ho Park, M.D.1, Ryan Oh, M.D.1, Sang-Oh Lee, M.D.1, Yang Soo Kim, M.D.1, Jun Hee Woo, M.D.1, Mi-Na Kim, M.D.2 and Sang-Ho Choi, M.D.1
Department of Internal Medicine1 and Laboratory Medicine2, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Vol.40 Num.3 (p170~174)
Septic arthritis is an uncommon finding of invasive Aspergillosis. It can be caused by direct inoculation, post-surgical infection, and hematogenous spread. Articular aspergillosis often involves the knee. A 49-year-old man who received a liver transplant in China on two months ago, due to liver cirrhosis caused by hepatitis B virus was admitted because of left side hip pain. Hip MRI showed joint effusion and bony destruction of the left hip and acetabulum. Incision and drainage was done and Aspergillus fumigatus was isolated from the resected tissue. After eight weeks of amphotericin B therapy, total hip replacement arthroplasty was done. Oral itraconazole 400mg/day was prescribed for six months after operation. The patient is now doing well without physical restriction
Keywords : Aspergillus fumigatus, Infectious arthritis, Liver transplantation