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A Study of HHV-8 Seroprevalence in Korean Health Care Workers
Woo-Chul Joo, M.D.1, Yong-Jun Choi, M.D.1, Jae-Eun Park, M.D.1, Hye-Myung Lee1, Jin-Soo Lee, M.D.1 Moon-Hyun Cheong, M.D.1, Ji-Hye Moon2, and Soo-Mi Kim2
1Department of Internal Medicine, College of Medicine, Inha University, 2Department of Infection Control, Inha University, Inchon, Korea
Vol.40 Num.4 (p246~247)
HHV-8 virus is known to be associated with Kaposi's sarcoma (KS) in HIV seropositive patients and its seroprevalence has geographic difference. In South Korea, incidence of KS is low not only in general population but also in HIV patients compared to other countries. It is speculated that low seroprevalence of HHV-8 has contributed to the low incidence of KS in South Korea. We examined the seroprevalence of anti HHV-8 IgG of HIV seronegative health care workers in one University hospital. Enzyme-linked immunosorbent assay(ELISA) was used for diagnosis. One person (0.6%,1/164) was seropositive, six were equivocal (3.7%,6/164) and 157 people were seronegative (95.73%,157/164). This study revealed that seroprevalence of HHV-8 in general population was low in South Korea. Further studies are needed to be carried out to evaluate the low HHV-8 seroprevalence in Korea.
Keywords : Herpesvirus 8, Hunman, Seroprevalence, Korea