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Original Articles
Compliance with Atovaquone-Proguanil against Malaria of Korean Travelers Abroad
Nak Hyun Kwon, M.D.1, Tae Soo Park, M.D.2, Hyo Sung Kang, M.D.1, Sung Hoon Kim, M.D.1, Lae Seok Hwang, M.D.1, Hye Jin Noh, M.D.1, * Ji Hwan Bang, M.D.1, 3, Jae Yoon Kim, M.D.2, 3 and Hyoung Shik Shin, M.D.1, 3
1Department of Internal Medicine, 2Department of Pediatrics, 3International Travelers' Clinic, National Medical Center, Seoul, Korea *Current Affiliation : Cardiac & Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine
Vol.40 Num.5 (p255~258)
Background : Recently, many Korean people travel abroad where malaria is prevalent. However, in Korea, relatively little is known about compliance of chemoprophylaxis against malaria. This study was performed to determine the factors influencing compliance of chemoprophylaxis against malaria in Korean travelers.
Materials and Methods : Face to face interview, telephone interview and e-mail correspondence were performed to 241 people who were prescribed with atovaquone-proguanil at the international travelers' clinic of National Medical Center between February 2007 and October 2007.
Results : Total of 55 people out of 235 reported one or more events of adverse reactions after chemoprophylaxis (total 76 events). However, in 38 adverse events the link between chemoprophylaxis and adverse events were very weak. Compliance of malaria chemoprophylaxis with atovaquone-proguanil was 53.9% in the study group. The predictive factors for non-compliance were package tour, travel of business affair and young age group.
Conclusions : Compliance of malaria chemoprophylaxis in Korea travelers was low compared with Dutch and French studies. More efforts to increase compliance are needed, especially in travelers on package tour, business travel and people under age 40.
Keywords : Travel, Malaria, Chemoprophylaxis, Compliance, Atovaquone-proguanil