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Two Cases of Bacteremia Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus
Jung Hyun Kim, M.D.1, Eun Jung Kang, M.D.1 , Yun Seok Jung, M.D.1 , Min Hyeok Jeon, M.D.1, Tae Hyong Kim, M.D.1, Hue Bong Sin, M.D.2 , Su Jin Park3 and Eun Ju Choo, M.D.1
Department of Internal Medicine1, Laboratory Medicine2, Soonchunhyang University School of Medicine, Bucheon
Vol.41 Num.1 (p58~61)
Center for Antimicrobial Resistance and Microbial Genetics3, University of Ulsan, Seoul, Korea Recent reports have described an increasing incidence of community-associated methicillinresistant Staphylococcus aureus (CA-MRSA) in patients who do not exhibit established risk factors for healthcare exposure. We report two cases of CA-MRSA bacteremia complicated by vertebral osteomyelitis. Both of CA-MRSA isolates were resistant to beta-lactam agents, but susceptible to clindamycin, trimethoprim-sulfamethoxazole, gentamicin, ciprofloxacin, and tetracycline. Both isolates carried staphylococcal cassette chromosome mec (SCCmec) type IVA, and were identified as sequence type (ST) 72 by mlultilocus sequence typing (MLST). However, the Panton-Valentine leukocidin (PVL) gene was not identified.
Keywords : Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), Bacteremia