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Primary Anti-retroviral Resistance in Treatment-naive HIV-infected Patients: A Korean HIV/AIDS Cohort Study
Joon Young Song, M.D.1, Jin Soo Lee, M.D.2, Hye Won Jung, M.D.3, Hee Jung Choi, M.D.4, Jin Seo Lee, M.D.5,
Division of Infectious Diseases, Department of Internal Medicine1, Korea University College of Medicine, Seoul, Division of Infectious Diseases, Department of Internal Medicine2, Inha University College of Medicine, Incheon, Division of Infectious Diseases, Department of Internal Medicine3, Chungbuk National University College of Medicine, Cheongju, Division of Infectious Diseases, Department of Internal Medicine4, Ewha University College of Medicine, Seoul, Division of Infectious Diseases, Department of Internal Medicine5, Hallym University College of Medicine, Seoul, Korea
Vol.41 Num.4 (p230~232)
Primary anti-retroviral resistance is considered one of the major problems of HIV treatment. Contrary to reports from western countries, prior Korean studies have reported a relatively low primary resistance rate (less than 5%). Based on Korean HIV/AIDS cohort data, we estimated the primary resistance rate among treatment-nave HIV- infected patients. According to the results, the primary resistance rate was higher (8.8%) than reported previously in Korean studies. However, the major PI mutation was not found.
Keywords : HIV, Antiretroviral therapy, Drug resistance