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Case Reports
Cardiac Involvement of Diffuse Large B Cell Lymphoma in a Patient with AIDS
Yoon Hee Jun1, GoHeun Kim1, So Yun Yun1, Yook Bum Pyun1, Young Chul Moon1, Dong Eun Song2 and Hee Jung Choi1
Division of Infectious Disease1, Departments of Internal Medicine and Pathology2, Ewha Womans University School of Medicine, Seoul, Korea
Vol.42 Num.1 (p51~56)
AIDS related malignancies have gradually decreased after the introduction of highly active antiretroviral therapy (HAART). Nevertheless, non-Hodgkin’s lymphoma is still a major malignancy in resource limited countries that have difficulty supplying HAART, and same holds true for Korea. We report a case of non-Hodgkin’s lymphoma involving the heart in a Korean AIDS patient, who presented with sudden arrhythmia and superior vena cava syndrome. He was diagnosed with AIDS in 2008, but refused to receive HAART. Immunohistologic findings were compatible diffuse large B cell lymphoma, and futher studies demonstrated involvement of the liver, adrenal gland, heart, and pericardiac space. HAART was initiated and non Hodgkin’s lymphoma was successfully managed with intensive chemotherapy. This is the first cardiac involvement non Hodgkin’s lymphoma in AIDS patients in Korea.
Keywords : Non-Hodgkin’s Lymphoma, HIV/AIDS, Superior Vena Cava syndrome