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 Case Reports |
| Pneumonia Caused by Corynebacterium macginleyi in HIV-infected Patient |
| Ji An Hur1, Sang-il Kim2 |
| 1The Division of Infectious Diseases, Department of Internal Medicine, The Yeungnam University of Korea, Daegu; 2The Division of Infectious Diseases, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea |
Vol.42 Num.5 (p319~322)
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Corynebacterium macginleyi is usually isolated from the eye surfaces and causes
ocular infections such as conjunctivitis, keratitis, and endophthalmitis. However,
cases that describe C. macginleyi as the causative agent for significant and lifethreatening infections in immunocompromised patients are increasingly reported.
Herein we report the first documented case of C. macginleyi pneumonia in a
human immunodeficiency virus (HIV) patient. A 42-year-old homosexual man
with HIV infection was hospitalized with a 1-month history of fever and dry cough.
Chest radiograph revealed ill defined ground glass opacities in both lung fields.
Methenamine silver stain of bronchoalveolar lavage fluid was negative. He showed
clinical improvement after treatment with trimethoprim/sulfamethoxazole and
prednisolone for three weeks, and was discharged. One month later, he presented
with dyspnea and more progressive pulmonary infiltrations. Bronchial washing
fluid culture yielded >100,000 colonies/mL of C. macginleyi , and he was given a
14-day course of antibiotic therapy with vancomycin, after which the patient fully
recovered. This case suggest the importance of not overlooking the significance of
positive cultures for C. macginleyi obtained from representative clinical samples in
patients with signs and symptoms of bacterial infection. |
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Keywords : Corynebacterium macginleyi , Pneumonia, Human immunodeficiency |
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